Generation ofFgfr1 conditional knockout mice
نویسندگان
چکیده
منابع مشابه
Generation of Fgfr3 Conditional Knockout Mice
Fibroblast growth factor receptor 3 (FGFR3), highly conserved in both humans and murine, is one of key tyrosine kinase receptors for FGF. FGFR3 is expressed in different tissues, including cartilage, brain, kidney, and intestine at different development stages. Conventional knockout of Fgfr3 alleles leads to short life span, and overgrowth of bone. In clinic, human FGFR3 mutations are responsib...
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ژورنال
عنوان ژورنال: genesis
سال: 2002
ISSN: 1526-954X,1526-968X
DOI: 10.1002/gene.10028